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目的研究榄香烯抗肿瘤的作用机制。方法用流式细胞仪和琼脂糖电泳检测DNA断裂，透射电镜观察超微结构变化。结果260μmol·L-1榄香烯孵育K562细胞6、12、24、48h后流式细胞仪检测到逐渐增强的凋亡峰，电泳发现明显的阶梯状条带，电镜观察到染色体聚集、凋亡小体。结论榄香烯能诱导K562细胞凋亡。
Objective To study the anti-tumor mechanism of elemene. Methods DNA fragmentation was detected by flow cytometry and agarose gel electrophoresis, and ultrastructural changes were observed by transmission electron microscopy. RESULTS: After incubation with 260 μmol·L-1 elemene for 6, 12, 24, and 48 h, apoptotic peaks were detected by flow cytometry. Electrophoresis revealed a clear ladder, and electron microscopy revealed chromosome aggregation and apoptosis. Small body. Conclusion Elemene can induce apoptosis in K562 cells.