克罗米酚(clomiphene)是一种合成的非类固醇化合物,具有较强的抗雌激素作用,同时又有较弱的雌激素活性。自从Kistner与Greeblott等应用于人类,发现其能促进排卵后,此药已在临床上广泛使用,恢复排卵率高的可达70—80％,妊娠率达30—40％。我科自1980年至1984年,用克罗米酚(上海第六制药厂制品)治疗功能性无排卵型不孕症、多囊卵巢综合征、黄体功能不足等84例、225个周期。现将使用方法及结果报告如下。 Clomiphene is a synthetic non-steroidal compound with strong anti-estrogenic activity and weak estrogenic activity. Since Kistner and Greeblott applied to humans and found that it can promote ovulation, the drug has been widely used clinically, to restore ovulation rate up to 70-80%, the pregnancy rate of 30-40%. Our department from 1984 to 1984, with clomiphene (Shanghai sixth pharmaceutical products) treatment of functional anovulatory infertility, polycystic ovary syndrome, corpus luteum function 84 cases, 225 cycles. The use of methods and results are reported below.