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甲状腺髓样癌(MTC)极为少见,约占甲状腺癌的5％～10％。术前诊断较为困难。我院从1964年1月至1997年12月共收治甲状腺癌105例,其中MTC 7例,报告如下。 临床资料 1.一般资料 本组男性1例,女性6例,年龄22～55岁,平均36.2岁。病程3个月至10年不等。就诊时主要临床表现为颈部肿块,其中单侧6例,双侧1例;颈部肿大淋巴结2例;伴声音嘶哑2例,心慌、面部潮红2例;慢性腹泻1例。全组病例均无家系发病史。 2.诊断、治疗与结果 除1例术前诊断为甲状腺癌外,余均为甲状腺良性肿瘤。 本组病例均作甲状腺腺叶切除,加一侧或双侧颈大块清扫术。其中2例作Ⅰ期手术,5例作Ⅱ期手术即先作肿块切除,后根据组织病理学检查结果,再作颈大块根治术。全部病例术后均未作任何其他治疗。
Medullary thyroid cancer (MTC) is extremely rare and accounts for 5% to 10% of thyroid cancer. Preoperative diagnosis is more difficult. In our hospital from January 1964 to December 1997, a total of 105 cases of thyroid cancer were treated, including 7 cases of MTC. The report is as follows. Clinical data 1. General information This group of 1 males and 6 females, aged 22 to 55 years, mean 36.2 years old. Duration varies from 3 months to 10 years. The main clinical manifestations at the time of treatment were neck masses, including unilateral in 6 cases and bilateral in 1 case; enlarged neck in 2 cases; hoarseness in 2 cases; palpitation and facial flushing in 2 cases; chronic diarrhea in 1 case. There was no history of family history in all cases. 2. Diagnosis, treatment and results Except for 1 case of preoperative diagnosis of thyroid cancer, the rest were thyroid benign tumors. This group of patients were treated with thyroidectomy, plus one or both sides of the neck dissection. Among them, 2 patients underwent stage I surgery, and 5 patients underwent stage II surgery. The tumors were resected first, and then the results of histopathological examination were used for radical mastectomy. None of the patients had any other postoperative treatment.