披针叶黄华(Thermopsis lanceolata R.Brown)总生物碱有骨胳肌松弛作用,但我院在分离肌松有效成分时得到一种使骨胳肌兴奋的结晶,经鉴定为鹰爪豆碱[(+)-spartine,Pachycarpine]。文献报道,本品及其左旋异构体有兴奋子宫、阻断神经节及减慢心率作用,曾用于分娩困难,心律不齐,阵发性心动过速及心房纤颤等。鹰爪豆碱的骨胳肌的兴奋作用尚未见报道,故我们对其进行了骨胳肌兴奋作用的初步研究。 The total alkaloid of Thermopsis lanceolata R. Brown has skeletal muscle relaxation, but in our hospital, when the active ingredients of muscle relaxant are isolated, a crystal that excites the skeletal muscle is obtained, which has been identified as sparrotoxin [( +) - spartine, Pachycarpine]. Reported in the literature, the goods and their left-isomers excited uterus, block the role of the ganglion and slow down the heart rate, used for delivery difficulties, arrhythmia, paroxysmal tachycardia and atrial fibrillation. The excitatory effects of sparodonin skeletal muscle have not been reported yet, so we conducted a preliminary study on the excitatory effect of skeletal muscle.