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本文报告一例并发颅内病变的细胞增殖性蓝痣(cellular blue nevus)的6岁男孩。在出生时即见到头部的青斑。1岁以后开始隆起,所以在3岁时进行了肿瘤切除。病理检查为细胞增殖性蓝痣。在此时的头部CT片上沿小脑幕仅见有索条状阴影,因尚无中枢神经系统症状而进行观察。到5岁时的CT 扫描上已看到了在中颅窝的高密度病变,故入脑神经科作了开颅手术。术中见颞骨与硬脑膜之间出现了黑色肿瘤,硬脑膜黑而变厚,软脑膜也见到黑色素的沉着。颞骨的板障及导血管孔找到了肿瘤细胞。肿瘤的组织学:是由与蓝痣一样的硬化部和含少量色素的细胞二相构成。电镜见到充满成熟的黑素小体和含少量各阶段的黑素小体的细胞。作者结合病例并以发病的病理为中心进行了讨论。
This article reports a 6-year-old boy with a cellular blue nevus with intracranial lesions. See the head of the green spots at birth. 1 year after the beginning of the bulge, so at the age of 3 had a tumor resection. Pathological examination for cell proliferation blue mole. At this point of the head of the CT film along the cerebellum saw only a strip of shadow, because there is no central nervous system symptoms were observed. To 5 years old CT scan has seen in the high-density lesions in the cranial fossa, so into the cranial neurology for craniotomy. See intraoperative temporal bone and dura between the black tumor, black and thicker dura, pia malady also see melanin calm. Temporal bone barrier and vascular access found tumor cells. Tumor histology: is composed of sclerenchyma-like sclerosis and a few pigmentary cells. Electron microscopy to see full of mature melanosomes and melanosomes containing a small number of cells at various stages. The authors combined the cases and discussed the pathogenesis of the disease.