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目的探讨少年儿童Stargardt病荧光素眼底血管造影改变与临床表现的联系。方法总结分析11例22眼Stargardt病的临床和荧光素眼底血管造影资料。结果0．1以下者4眼,0．1～0．5的13眼,0．5以上的5眼,眼底改变可见中心凹反射消失、色素紊乱、金箔样萎缩病灶及黄白色渗出斑点。FFA所见：黄斑区园盘状、环状或椭圆形的1．5～2．5PD大小透见荧光8眼,有点状荧光遮蔽黄斑区不规则透见荧光5眼,散在点状高荧光3眼,背景荧光不均6眼,11例均有脉络膜背景荧光遮蔽现象。结论此病FFA检查对早期诊断有重大意义。
Objective To investigate the relationship between changes of fundus fluorescein angiography and clinical manifestations in children with Stargardt’s disease. Methods The clinical data and clinical manifestations of fundus fluorescein angiography in 11 patients with Stargardt’s disease of 22 eyes were analyzed. Results 0.1 less than 4 eyes, 0.1 to 0.5 of 13 eyes, 0.5 more than 5 eyes, changes in the fundus disappear foveal reflection, pigment disorders, gold foil-like atrophy lesions and yellow-white oozing spots. FFA see: macular disc park, ring or oval 1.5 ~ 2.5PD size see through the fluorescence of 8 eyes, a bit like the fluorescence mask macular irregular see through fluorescence 5, scattered in the spot-like high fluorescence 3 There were 6 eyes with uneven fluorescence in the eye and 11 cases with choroidal background fluorescence occlusion. Conclusion FFA examination of this disease is of great significance to early diagnosis.