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成年雄性大鼠50只,分为正常组、脾虚组、自然恢复组和治疗组。观察小肠粘膜一般组织结构及粘膜内胃泌素细胞和5-羟色胺细胞的变化。结果表明:粘膜未见明显异常改变。脾虚组胃泌素细胞和5-羟色胺细胞分泌功能活跃,这可能与脾虚证候发生有关。经四君子汤治疗后,治疗组+++的胃泌素细胞数比自然恢复组更接近正常,说明四君子汤对脾虚证有一定治疗作用。
Fifty adult male rats were divided into normal group, spleen deficiency group, natural recovery group and treatment group. Observe the changes in the general tissue structure of the small intestine mucosa and gastrin and 5-hydroxytryptamine cells in the mucosa. The results showed no obvious abnormal changes in the mucosa. Gastrin and 5-hydroxytryptamine cells in the spleen deficiency group secrete active functions, which may be related to the occurrence of spleen deficiency syndrome. After treatment with Sijunzi Decoction, the number of gastrin cells +++ in the treatment group was closer to normal than that in the natural recovery group, indicating that Sijunzi Decoction has a certain therapeutic effect on spleen deficiency syndrome.