放射治疗是通过电离辐射照射肿瘤以及周围正常组织发生一系列的物理(如电离事件等)、化学(如自由基等)及生物效应(如DNA链的断裂等)。客观地说只要是在放疗就不可避免会产生放射性损伤,其中心脏损伤是放射治疗肺癌的放射剂量限制因素。放射性心脏损伤(radiation-induced heart disease,RIHD)[1]主要是指胸部肿瘤在放射治疗时因照射到心脏组织,从而产生心包炎、心肌纤维化、冠状动脉及传导系统损 Radiation therapy is a series of physical (such as ionization events), chemical (such as free radicals, etc.) and biological effects (such as DNA strand breaks, etc.) that occur through ionizing radiation exposure to tumors and surrounding normal tissues. Objectively speaking, radiotherapy is inevitable as long as radiotherapy is inevitable. Cardiac injury is a radiation dose limiting factor for radiotherapy of lung cancer. Radiation-induced heart disease (RIHD) [1] mainly refers to chest tumors in the radiation therapy due to irradiation to the heart tissue, resulting in pericarditis, myocardial fibrosis, coronary artery and conduction system damage