1935年德国首次报告从事铬(Cr)化合物制造业者的肺癌发生率显著增高;此后英美等国进行深入研究,但多系流行病学调查分析。作者从1974年开始对东京铬酸盐制造厂的86名男性工人进行痰细胞学及内镜检测随访,并在1892～1991年间对其中10例恶性肿瘤和1例脑梗塞死亡者作了剖检及肺内铬沉着量测定,着重探讨铬肺癌的病理学特征。 In 1935, Germany reported for the first time that the incidence of lung cancer in chromium (Cr) compounds was significantly higher; after that, Britain and the United States conducted in-depth studies, but many epidemiological investigations and analysis. The authors have conducted sputum cytology and endoscopic examinations of 86 male workers at the chromate manufacturing plant in Tokyo since 1974, and performed necropsy on 10 of them with malignancy and one death from cerebral infarction between 1892 and 1991. And the amount of chromium deposition in lungs, focusing on the pathological features of chromium lung cancer.