本实验观察在陕西省大骨节病高发区耀县4个乡11个村8所小学进行实验。观察对象7～14岁儿童。分组为硫酸锌组,食用硒盐组和硫酸锌硒组及对照组,4组情况比较均衡,可比性好。投药方法:采用北京制药广产硫酸锌粉加赋型剂淀粉制成含量100mg,150mg胶丸,硫酸锌组的观察对象,不分年龄每日100mg,连服半年,硒盐组:按村队户每人统一供应1/6万硒盐0.5kg食用;锌加硒 The experimental observation of Kashin-Beck disease in Shaanxi Province Yao County, 4 townships 11 villages 8 primary school experiments. Observed children aged 7 to 14 years. Divided into zinc sulfate group, selenium salt group and zinc selenium sulfate group and the control group, the four groups of more balanced situation, good comparability. Method of administration: using Beijing Pharmaceutical Guang Zinc sulfate plus excipient starch made of 100mg, 150mg capsules, zinc sulfate observed objects, regardless of age, daily 100mg, even for six months, selenium salt group: according to the village team Household uniform supply 1/6 million selenium salt 0.5kg consumption; zinc plus selenium