在曼氏、埃及和日本血吸虫三种人体血吸虫病的感染中,以感染日本血吸虫的肝内虫卵最多。动物组织病理学的资料亦提示宿主组织对日本血吸虫虫卵的反应远较其他两种为强。以日本血吸虫的4个株感染小白鼠所导致的肝脾肿大程度,不仅与肝内虫卵数的多少有关,而且亦与宿主组织对不同株的反应性有密切关系。因此,研究不同种或株的血吸虫虫卵对肝脏的损害,对阐明寄生虫与宿主间的关系具有重大意义。 In Man’s, Egyptian and Japanese schistosomiasis three human schistosomiasis infections, most of the intrahepatic worms infected with Schistosoma japonicum. Data from animal histopathology also suggest that the host tissue response to Schistosoma japonicum eggs is much stronger than the other two. Infection of mice with 4 strains of Schistosoma japonicum caused by hepatosplenomegaly is not only related to the number of eggs in the liver but also closely related to the host tissue response to different strains. Therefore, the study of different types or strains of schistosomiasis eggs on the liver damage, to elucidate the relationship between parasites and host is of great significance.