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目的探讨老年人垂体腺瘤(SPA)的手术疗效。方法总结经CT扫描或MRI确诊的56例SPA经蝶显微外科治疗的临床资料,35例经唇下-鼻中隔-蝶窦入路、21例经鼻前庭-鼻中隔-蝶窦入路行肿瘤切除术。结果本组微腺瘤7例,大腺瘤30例,巨大腺瘤19例,术后无死亡。48例获长期随访(平均3.5年),41例恢复良好;7例术后平均3.4年肿瘤复发,其中2例再次手术,5例采用药物、放疗或放射外科治疗,于3个月时复查见患者恢复较为满意。结论采取经蝶显微外科治疗SPA,是一种安全、有较的方法
Objective To investigate the surgical effects of elderly patients with pituitary adenomas (SPA). Methods The clinical data of 56 cases of SPA transsphenoidal microsurgery diagnosed by CT scan or MRI were summarized. Thirty-five patients underwent tumor resection through the sub-labial-nasal septum-sphenoid sinus approach and 21 cases via the nasal vestibular-septal septum-sphenoid sinus approach. Surgery. Results There were 7 cases of microadenomas, 30 cases of macroadenomas, and 19 cases of giant adenomas. No death occurred after surgery. 48 cases received long-term follow-up (mean 3.5 years), 41 cases recovered well; 7 cases had an average 3.4 years of tumor recurrence, of which 2 cases had reoperation and 5 cases were treated with drugs, radiotherapy, or radiosurgery, in 3 cases. The monthly review showed that the patient recovered more satisfactorily. Conclusion Adopting transsphenoidal microsurgery for the treatment of SPA is a safe and comparative method