中枢神经系统可分泌促红细胞生成素 (Epo) ,神经细胞表达大量的Epo受体 ,神经元的许多功能受Epo调控。Epo是中枢神经系统中一个新的信号转导分子 ,介导Epo受体信号通路。Epo对细胞内钙浓度有明显的调节作用 ,Epo还可以抑制神经细胞的凋亡 ,促进神经细胞的存活 The central nervous system secretes erythropoietin (Epo), while neurons express a large number of Epo receptors. Many functions of neurons are regulated by Epo. Epo is a new signal transduction molecule in the central nervous system that mediates the Epo receptor signaling pathway. Epo significantly regulate intracellular calcium concentration, Epo can also inhibit nerve cell apoptosis and promote the survival of nerve cells