粉防已碱(Tetrandrine,Tet)是从中药粉防已中提出的有效成分,单体为双苄基异喹啉衍生物,具有镇痛,消炎,抗风湿,抗过敏,抗心律失常,降压等作用,临床上已用于高血压的治疗,虽然五十年代吕富华等已证明Tet有治疗甲醛性关节炎的作用,但因条件限制,至今对其作用机制,尤其是抗炎作用机制仍不明确。为此。我们进行了一系列研究,目 Tetrandrine (Tet) is an active ingredient that has been proposed in Chinese medicine powder protection. The monomer is bis-benzylisoquinoline derivative, which has analgesic, anti-inflammatory, anti-rheumatic, anti-allergic, anti-arrhythmic, antihypertensive Other effects have been clinically used for the treatment of hypertension, although in the fifties Lv Fuhua et al. have demonstrated that Tet has a role in the treatment of formaldehyde-induced arthritis, but because of the limited conditions, the mechanism of action, especially the anti-inflammatory mechanism, has not yet been clear. to this end. We conducted a series of studies.