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本文报道了9例恶性血液病所观察到的i(7q)、i(11q)、i(17q)和i(21q)等臂染色体。作者认为等臂染色体的存在,在恶性变中可能起一定作用。本研究取9例白血病患者的骨髓、淋巴结和胸水细胞为材料,以直接法或短期培养法进行常规和G显带染色体制备,根据ISCN鉴别染色体并进行病例分类;白血病和异常粒细胞综合征按FAB标准;非何杰金氏淋巴瘤按专业方案;何杰金氏病按Lukes-Rye分类;恶性淋巴肿瘤的临床分期按Ann-Arbor分类。结果:例1、2、5和6均有i(7q)染色体标记。例1诊断为获得性特发性铁粒幼细胞性贫血(AISA),例2为急性粒细胞
In this paper, the isomerism chromosomes of i (7q), i (11q), i (17q) and i (21q) observed in 9 cases of hematologic malignancies were reported. The authors believe that the presence of the other arm chromosomes may play a role in malignant transformation. In this study, nine cases of leukemia patients bone marrow, lymph nodes and pleural effusion cells as material, direct or short-term culture of conventional and G-banding chromosome preparation, according to ISCN to identify chromosomes and case classification; leukemia and abnormal granulocyte syndrome by FAB criteria; non-Hodgkin’s lymphoma by specialty; Hodgkin’s disease by Lukes-Rye classification; clinical staging of malignant lymphomas by Ann-Arbor classification. Results: All cases 1, 2, 5 and 6 had i (7q) chromosomal markers. Example 1 was diagnosed as acquired idiopathic granulocytopenic anemia (AISA), case 2 was acute granulocyte