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目的总结难治性继发性甲状旁腺功能亢进症(secondary hyperparathyroidism,SHPT)患者腹主动脉钙化与心脏瓣膜钙化情况,分析其相关性。方法选择50例难治性SHPT患者,分别行腹部侧位X线和心脏彩超检测腹主动脉钙化和心脏瓣膜钙化情况,并分析其相关性。结果心脏瓣膜钙化分级越高者,腹主动脉钙化积分(abdom-inal aorta calcification score,AACS)相应越高。二尖瓣和主动脉瓣均钙化组AACS较单纯二尖瓣或主动脉瓣钙化组高,无钙化组AACS相对最低。AACS≤5分组与AACS>5分组二尖瓣钙化和主动脉瓣钙化情况差异有统计学意义(P值分别为0.007、0.001)。结论难治性SHPT患者腹主动脉钙化及心脏瓣膜钙化发生率高,且腹主动脉钙化与心脏瓣膜钙化有明显相关。
Objective To summarize the aortic calcification and valvular heart calcification in patients with refractory secondary hyperparathyroidism (SHPT). Methods Fifty patients with refractory SHPT were selected and examined for abdominal calcification and heart valve calcification by lateral abdominal X-ray and echocardiography. The correlations were also analyzed. Results The higher the heart valve calcification grade, the higher the abdominal aorta calcification score (AACS). AACS in mitral and aortic calcification group was higher than in simple mitral valve or aortic valve calcification group, while AACS in non-calcified group was the lowest. There was significant difference in mitral valve calcification and aortic valve calcification between AACS≤5 group and AACS> 5 group (P = 0.007,0.001, respectively). Conclusions The incidence of abdominal aorta calcification and heart valve calcification in patients with refractory SHPT is high, and abdominal aortic calcification is significantly associated with heart valve calcification.