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早在1984年就已发现人免疫缺陷病毒一I型（HIV－l）感染细胞是通过与细胞表面受体CDe结合而进行的，但两年后又发现表达CDe的非人类细胞不能被IlfV－l感染，因此有人认为仅有CDe作为H］V－l的受体是不够的，还必须有人类细胞特异表达的某种辅助因子。最近，一些与CDe偶联的HIV
As early as 1984, human immunodeficiency virus-I (HIV-1) infected cells were found to bind to the cell surface receptor CDe, but two years later it was found that non-human cells expressing CDe could not be infected with IlfV- Therefore, some people think that it is not enough to use only CDe as a receptor for H] V-1, and some cofactor specific for human cells must be available. Recently, some HIV conjugated to CDe