患者女,63岁。因面部及手足斑块进行性加重10年于2013年6月来我科就诊。患者10年前鼻部出现一豆大丘疹,渐扩大,偶有破溃流脓,未予处理。5年前下唇、手足部位相继出现类似皮疹,渐扩大。2年前曾在当地医院就诊,以“结核病”给予抗结核药物(具体不详)治疗1年,皮疹好转部分消退,后患者自行停药半年皮疹再次加重。患者自发病以来无发热、咳嗽等不适症状,精神、饮食、二便正常。患者20岁时曾患颈部瘰疬性皮肤结核;37岁时行胸椎结核手术;有高血 Female patient, 63 years old. Due to facial and hand-foot plaques progressive aggravating 10 years in June 2013 to our department. 10 years ago, a large nasal papules papules, gradually expanding, occasionally ulcerated pus, not treated. 5 years ago, the lower lip, hand and foot parts have similar rash, gradually enlarged. 2 years ago in a local hospital for treatment, “tuberculosis” given anti-TB drugs (specific unknown) for 1 year, partial improvement of the rash disappeared, the patient stopped their own drug six months after rash aggravated again. Since the onset of patients without fever, cough and other symptoms, mental, diet, two will be normal. At 20 years of age, the patient had cervical 瘰 疬 of cutaneous tuberculosis; 37-year-old thoracic tuberculosis surgery; high blood