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胰岛移植治疗Ⅰ型糖尿病已为国内外新开展的研究课题,在理论上能治疗糖尿病、防止和阻止糖尿病并发症的发生和发展,作者已治疗4例,近期效果良好。胰岛移植虽能纠正异常糖代谢,但移植时应注意:①移植物的数量以6～8个胎胰为宜;②经培养的胎胰组织7～10天最佳;③移植于小腹腔和大网膜囊符合正常生理途径;④使用免疫抑制剂,防止排异反应;⑤在治疗时应密切观察病情和血糖变化,以调节胰岛素用量;凡出现低血糖样表现者,说明移植物已在受体内成活,并出现功能。
Islet transplantation for the treatment of type I diabetes has become a new research topic at home and abroad, in theory, can treat diabetes, prevent and prevent the occurrence and development of diabetic complications, the authors have been treated in 4 cases, the recent good results. Although islet transplantation can correct abnormal glucose metabolism, but transplantation should pay attention to: ① the number of grafts to 6 to 8 fetal preparation is appropriate; ② cultured fetal pancreatic tissue 7 to 10 days the best; ③ transplanted in the abdominal cavity and Omental sac in line with normal physiological pathways; ④ use of immunosuppressive agents to prevent rejection; ⑤ in the treatment should be closely observed disease and blood glucose changes in order to adjust the amount of insulin; where hypoglycemia-like performance, that the graft has been Recipients survive and function.