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应用ELISA方法检测了28例小儿支气管哮喘发作时血清IL－8含量。结果发现支气管哮喘患儿血清IL－8含量为415．6±291．50pg／ml，明显高于正常对照组85．25±39．54pg／ml，而且重症患儿血清IL－8含量637．35±360．19pg／ml明显高于轻症患儿162．11±63．54pg／ml。当哮喘发作会并感染时，血清IL-8含量562．17±356．67pg／ml，高于不伴感染哮喘患儿183．5±116．58pg／ml。因此我们认为，儿童支气管哮喘时，IL－8合成释放增加，可能参与了哮喘的发病机制，血清IL－8的检测为判断病情，了解有无感染；提供了一个较好的实验参数。`
Serum IL-8 levels in 28 children with bronchial asthma were detected by ELISA. The results showed that serum IL-8 level in children with bronchial asthma was 415.6 ± 291.50pg / ml, which was significantly higher than that of the normal control group (85.25 ± 39.54pg / ml), and the serum IL-8 level was 637.35 ± 360.19pg / ml was significantly higher than 162.11 ± 63.54pg / ml in mild children. When the asthma attack and infection, serum IL-8 levels 562.17 ± 356.67pg / ml, higher than 183.5 ± 116.58pg / ml in children without infection with asthma. Therefore, we believe that children with bronchial asthma, IL-8 release increased, may be involved in the pathogenesis of asthma, serum IL-8 test to determine the condition, to understand whether there is infection; provides a better experimental parameters. `