Th1/Th2细胞因子网络平衡的失衡 ,尤其是Th2细胞因子异常高表达在变应性鼻炎等呼吸道炎症反应中有重要的作用。了解诱导Th2细胞极化的因素 ,多信号参与的复杂过程 ,局部微环境、转录因子和生活环境等的重要作用及了解Th2细胞极化的机制 ,对调节Th1/Th2细胞因子失衡 ,减轻Th2细胞优势的炎症反应 ,对变应性鼻炎等呼吸道变应性疾病进行特异性免疫治疗具有重要意义 The imbalance of Th1 / Th2 cytokine network balance, especially the abnormally high expression of Th2 cytokines plays an important role in respiratory inflammation such as allergic rhinitis. To understand the factors that lead to the polarization of Th2 cells, the complex process of multi-signal involved, the local microenvironment, transcription factors and living environment and the important role of understanding the mechanism of Th2 cell polarization, regulating Th1 / Th2 cytokine imbalance, reducing Th2 cells Advantages of inflammatory response to allergic rhinitis and other respiratory allergic diseases, immunotherapy is of special significance