论文部分内容阅读
目的探索接触金属加工液(metal working fluids,MWF)对工人肺通气功能的影响。方法对某机械加工车间工龄满1年的工人进行健康体检,并根据工作场所空气中MWF浓度对工人进行分组,≤1mg/m3者为低浓度组,>1mg/m3为高浓度组。利用logistic回归模型进行多因素分析,并利用比例风险模型计算肺通气功能异常影响因素的患病比(PR值)。结果高浓度组肺通气功能异常率为18.1%,低浓度组肺通气功能异常率为9.7%,差异有临界统计学意义(χ2=3.13,P=0.077)。logistic回归分析显示接触MWF的OR值为2.49(1.00~6.20),比例风险模型计算的患病比(PR值)为1.88(0.89~3.95)。结论 MWF暴露可能使肺通气功能异常率增加。应制定相应的标准和防治规范,使MWF的监测、监督和治理纳入目前的管理体系。
Objective To explore the effect of metal working fluids (MWF) on pulmonary ventilation in workers. Methods The workers in a mechanical workshop with a working life of one year were given a physical examination and the workers were grouped according to the MWF concentration in the workplace. The concentration of ≤1mg / m3 for the low concentration group and> 1mg / m3 for the high concentration group. Multivariate analysis was performed using a logistic regression model, and the odds ratio (PR) was used to calculate the prevalence of ventilatory dysfunction. Results The abnormal rate of pulmonary function was 18.1% in high concentration group and 9.7% in low concentration group, the difference was statistically significant (χ2 = 3.13, P = 0.077). Logistic regression analysis showed that the OR of contact MWF was 2.49 (1.00-6.20), and the proportional hazard model (PR) was 1.88 (0.89-3.95). Conclusions MWF exposure may increase the abnormal rate of pulmonary ventilation. The corresponding standards and prevention and control norms should be formulated so that the monitoring, supervision and control of MWF can be incorporated into the current management system.