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目的:探讨应用干扰素治疗小儿秋季腹泻49例的临床效果。方法:选择2岁以下符合秋季腹泻的小儿91例,随机分成治疗组和对照组。治疗组应用干扰素治疗,对照组应用病毒唑、庆大霉素进行常规治疗;同时分别观察2组患儿并发症,水、电解质平衡情况以及平均治愈时数,进行统计学处理。结果:治疗组49例患儿总有效率为90.1%;对照组42例患儿总有效率为85.6%,2组患儿观察指标对比具有统计学意义(P<0.05)。结论:早期应用干扰素治疗病毒性肠炎可缩短病程,促进胃肠功能恢复有一定疗效,而且未见任何毒副作用,值得广泛推广。
Objective: To investigate the clinical effect of interferon in treating 49 children with autumn diarrhea. Methods: Ninety-one children with diarrhea under 2 years old were selected and randomly divided into treatment group and control group. The treatment group was treated with interferon, while the control group was given ribavirin and gentamicin for routine treatment. The complication, water and electrolyte balance, and the average cure time were also observed in the two groups for statistical analysis. Results: The total effective rate of 49 children in the treatment group was 90.1%. The total effective rate of the 42 children in the control group was 85.6%. There were significant differences between the two groups (P <0.05). Conclusion: The early use of interferon in the treatment of viral enteritis can shorten the course of the disease and promote the recovery of gastrointestinal function with a certain effect, but without any side effects, it is worth widely disseminated.