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目的探讨复方米非司酮配伍米索前列醇终止10～14周妊娠的临床效果。方法选取60例行药物流产的孕10～14周孕妇，所有孕妇均给予口服复方米非司酮配伍米索前列醇，观察临床效果。结果本组60例行药物流产孕妇中完全流产47例，不完全流产5例，失败8例，流产成功率为86.7%。治疗过程中部分患者出现胃纳差、腹泻症状，未经特殊处理，症状自行消失。结论采用复方米非司酮配伍米索前列醇终止10～14周妊娠临床效果好，安全性高，值得临床进一步推广使用。“,” Objective To investigate the clinical effect of compound mifepristone combined with misoprostol for termination of 10~14 weeks of pregnancy. Methods 60 cases of drug abortion pregnant women during 10 ~ 14 weeks of gestation in our hospital was selected, al pregnant women were given oral compound mifepristone and misoprostol, observe clinical effect. Results In the 60 cases, complete abortion of 47 cases, incomplete abortion of 5 cases of, 8 cases failed, the abortion success rate was 86.7%. Some patients occured poor appetite and diarrhea during treatment, symptoms disappeared without special treatment. Conclusion Taking compound mifepristone combined with misoprostol for termination of 10 ~ 14 weeks of pregnancy has good clinical effect, high safety, it is worthy of further clinical application.