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目的探讨米非司酮片配伍卡前列甲酯栓舌下含服药物流产的临床效果。方法选择三组符合门诊药物流产要求的病例共229例,Ⅰ组(73例)米非司酮片配伍米索前列醇片口服、Ⅱ组(48例)米非司酮片配伍卡前列甲酯栓舌下含服、Ⅲ组(108例)米非司酮片配伍卡前列甲酯栓阴道放药,通过观察各组末次用药至胎囊排出的时间(时间差),进行比较分析。结果Ⅰ组与Ⅱ组、Ⅲ组相比,从末次用药到胎囊排出的时间最短,在统计学上有显著差异(双侧Sig.<0.05);Ⅱ组与Ⅲ组相比,从末次用药到胎囊排出的时间,在统计学上无显著差异(双侧Sig.>0.05)。结论米非司酮片配伍卡前列甲酯栓舌下含服的效果并不优于米非司酮片配伍米索前列醇片口服和配伍卡前列甲酯栓阴道放药,米非司酮片配伍米索前列醇片口服具有更显著的效果。
Objective To investigate the clinical effect of mifepristone tablets combined with carbamachidine suppository drug abortion. Methods A total of 229 cases were selected according to the requirements of outpatient medical abortion. Group Ⅰ (73 cases) were treated with mifepristone tablets and misoprostol tablets orally, and group Ⅱ (48 cases) mifepristone tablets combined with carbamazepine Sublingual sublingual, Group III (108 cases) mifepristone tablets combined with carbamazepin suppository vaginal discharge, by observing each group last administration to the time of fetal discharge (time difference), comparative analysis. Results Compared with group Ⅱ and group Ⅲ, group Ⅰ showed the shortest discharge time from the last administration to the fetal sac, with a statistically significant difference (Sig> 0.05). In group Ⅱ, compared with group Ⅲ, There was no statistically significant difference in timing of discharge to the fetal sac (bilateral Sig.> 0.05). Conclusion The effect of mifepristone tablets combined with cardinal methylester sublingual administration is not superior to that of mifepristone tablets combined with misoprostol tablets oral and compatibility card tops methyl ester suppositories vaginal drug, mifepristone tablets Oral administration of misoprostol tablets have a more significant effect.