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对33例所谓“肺乳头状瘤型炎性假瘤”进行了肉眼、光镜及免疫组化观察,并从NSE染色阳性中选出10例进行了电镜观察。结果表明:肺神经内分泌瘤20例(60.6%);肺乳头状瘤型炎性假瘤7例(21.2%);肺泡Ⅱ型细胞乳头状腺瘤3例(9.1%),不能分类者3例(9.1%)。结果提示:“肺乳头状瘤型炎性假瘤”是至少包括3种病变的一组病变群,而且肺硬化性血管瘤可能是假象,本质也是肺神经内分泌瘤。同时,对肺的神经内分泌瘤、乳头状瘤型炎性假瘤及Ⅱ型细胞乳头状腺瘤的病理诊断及鉴别诊断进行了讨论。
Thirty-three cases of so-called “pulmonary papilloma-type inflammatory pseudotumor” were observed by naked eye, light microscopy, and immunohistochemistry. Ten cases were selected from the positive NSE staining for electron microscopy. The results showed that there were 20 cases (60.6%) of pulmonary neuroendocrine tumors, 7 cases (21.2%) of pulmonary papilloma-type inflammatory pseudotumor, and 3 cases (9.1%) of alveolar type II cells papillary adenomas. There were 3 cases (9.1%) who could not be classified. The results suggest that “pulmonary papilloma-type inflammatory pseudotumor” is a group of lesions including at least 3 types of lesions, and pulmonary sclerosing hemangiomas may be illusions, and in essence they are pulmonary neuroendocrine tumors. At the same time, the pathological diagnosis and differential diagnosis of pulmonary neuroendocrine tumors, papillomatous inflammatory pseudotumors, and type II cell papillary adenomas were discussed.