运用设备比对及改进初筛设备降低血液ALT报废率

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目的通过对丙氨酸氨基转移酶(ALT)临界值报废血液的研究分析,确定设备间不精密度的叠加,可能导致ALT临界值血液报废,研究运用设备比对方法,减少血液ALT报废率。方法将体采科采血车分两组,其中一组为3、5、6号采血车,该组将ALT初筛设备与复检设备定期进行比对,并根据结果对设备进行调整。另一组为1、2、7、8号采血车,该组只是按照常规将ALT初筛设备定期校准,并使用室内质控品对精密度进行监测,未与复检设备定期进行比对,比较两采血车的ALT报废率。结果 2008年8—11月,未进行设备比对的1、2、7、8号采血车ALT报废率为0.92%,已进行设备比对的3、5、6号采血车ALT报废率为0.48%。两者比较,χ2=7.15,P<0.01,差异有统计学意义,已进行设备比对的采血车的ALT报废率较未进行设备比对的采血车的报废率明显下降。结论说明将ALT初筛设备与复检设备定期进行比对,并根据结果对设备及时进行调整,能够明显降低血液ALT报废率。 OBJECTIVE: To study the ALT cut-off value of blood, to determine the superimposition of imprecision between devices, which may result in the blood loss of ALT threshold. To study and compare the methods to reduce the ALT rejection rate. Methods The body blood collection car was divided into two groups, one of which was blood car No. 3, 5 and 6. The group regularly compared the ALT screening equipment with the recheck equipment and adjusted the equipment according to the result. The other group is 1,2,7,8 blood collection car, the group is routinely ALT screening equipment regularly calibrated, and the use of indoor quality control to monitor the precision, and the re-inspection equipment is not regularly compared, Compare ALT scrap rates for two blood collection vehicles. Results From August to November in 2008, the ALT rejection rate of blood collection vehicles 1, 2, 7, and 8 without equipment comparison was 0.92%. The ALT rejection rate of blood collection vehicles Nos. 3, 5 and 6 that had been compared with equipment was 0.48 %. The difference between the two was χ2 = 7.15, P <0.01, the difference was statistically significant. The ALT rejection rate of the blood collection vehicles that had been compared with the equipment was significantly lower than that of the blood collection vehicles without the equipment comparison. Conclusions The ALT screening device and the recheck device are periodically compared, and the device is adjusted according to the result in time, which can obviously reduce the blood ALT rejection rate.
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