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对65例 NIDDM 患者红细胞膜脂质成分.红细胞变形能力进行测定.结果表明:NIDDM患者红细胞膜胆固醇、胆固醇/磷脂比值、过氧化脂质明显升高,膜磷脂和红细胞变形能力降低,上述改变在 NIDDM 伴有视网膜病变者更为显著;直线相关分析红细胞变形能力降低和红细胞膜脂质成分改变存在明显相关性。提示糖尿病红细胞膜脂质成分改变可能是导致红细胞变形能力降低的一重要因素.
The erythrocyte deformability of erythrocyte membrane in 65 cases of NIDDM patients was determined.The results showed that the erythrocyte membrane cholesterol, cholesterol / phospholipid ratio, lipid peroxidation and the deformability of membrane phospholipids and erythrocytes were decreased in NIDDM patients NIDDM patients with retinal lesions were more significant; linear correlation analysis of erythrocyte deformability and erythrocyte membrane lipid composition changes were significantly correlated. Tip changes in diabetic lipid membrane lipid composition may lead to decreased erythrocyte deformation an important factor.