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库肯勃(Krukenberg)瘤是一种恶性程度极高的卵巢转移性肿瘤,占所有卵巢肿瘤的1%~2%。该肿瘤以富含黏液的印戒细胞样肿瘤细胞浸润、间质肉瘤样增生为特点,预后极差~([1,2])。Krukenberg瘤临床及病理表现多样,大部分病例以卵巢肿瘤为首发症状,部分患者年轻,病理形态不典型,造成术中冷冻切片诊断困难,需引起临床及病理医师重视。本文对北京大学人民医院诊治的21例Krukenberg瘤进行临床病理特点分析并复习文献,以增强对该肿瘤的认识。
Krukenberg’s tumor is a highly malignant ovarian metastatic tumor that accounts for 1% to 2% of all ovarian tumors. The tumor is characterized by mucinous signet ring cell-like tumor cells infiltration, interstitial sarcomatoid hyperplasia, poor prognosis ~ ([1,2]). Krukenberg tumor clinical and pathological performance varied, most cases of ovarian tumors as the first symptom, some patients young, pathological atypia, resulting in intraoperative frozen section of the diagnosis difficult to be caused by clinicians and pathologists attention. In this paper, Peking University People’s Hospital diagnosis and treatment of 21 cases of Krukenberg tumor clinicopathological features and review the literature to enhance awareness of the tumor.