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目的探讨癌症继发性血栓性微血管病(TM)的诊断标准,分析误诊原因。方法对6例误诊癌症继发TM的临床特点及实验室检查结果进行分析。结果误诊为血栓性血小板减少性紫癜(TTP)2例,溶血尿毒综合征(HUS)、Evans综合征、播散性血管内凝血(DIC)、Coombs试验阴性的自身免疫性溶血性贫血(AIHA)各1例。结论应提高对本病的认识,对临床表现与实验室资料的综合判断和分析是提高确诊率的基本手段。
Objective To investigate the diagnostic criteria of secondary thrombotic microangiopathy (TM) and to analyze the causes of misdiagnosis. Methods The clinical features and laboratory test results of 6 cases of misdiagnosis of secondary cancer were analyzed. The results were misdiagnosed as 2 cases of thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS), Evans syndrome, disseminated intravascular coagulation (DIC), autoimmune hemolytic anemia (AIHA) with negative Coombs test. One case each. Conclusion The knowledge of the disease should be improved. Comprehensive judgment and analysis of clinical manifestations and laboratory data are the basic means to increase the diagnosis rate.