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目的:分析评价应用导管介入技术治疗子宫肌瘤和宫颈癌的临床疗效。方法:选择19例子宫肌瘤、13例宫颈癌皆经一侧股动脉入路,行两侧子宫动脉插管,对肌瘤者分别选择KMG、PVA微球或碘化油+平阳霉素乳剂,栓塞阻断其血供;宫颈癌者应用明胶海绵颗粒+抗癌药物行手术前灌注栓塞辅助治疗。结果:19例子宫肌瘤、13例宫颈癌共64支子宫动脉均插管成功并栓塞,同时对宫颈癌行双侧髂内动脉和子宫动脉抗癌药物灌注,19例子宫肌瘤经3~12个月随访,平均瘤体缩小率59.4%,多发者中的部分小肌瘤消失,1例坏死脱落,临床症状明显改善;13例宫颈癌介入治疗3周后手术切除顺利,标本组织学示癌巢趋向消失,周边组织有淋巴细胞浸润,部分宫颈恢复正常,其中2例癌组织消失,本组32例介入治疗后皆无严重并发症发生。结论:介入治疗子宫肌瘤安全、微创且疗效肯定;对宫颈癌术前介入可有效提高手术切除率和降低复发率,值得临床广泛应用。
OBJECTIVE: To analyze and evaluate the clinical efficacy of catheterization in the treatment of uterine fibroids and cervical cancer. Methods: Nineteen cases of uterine fibroids and 13 cases of cervical carcinoma were treated by one side femoral artery. Uterine artery was cannulated on both sides. KMG, PVA microspheres or iodized oil + pingyangmycin emulsion , Embolism blocked its blood supply; cervical cancer patients with gelatin sponge particles + anticancer drugs preoperative perfusion embolization adjuvant therapy. Results: 19 cases of uterine fibroids, 13 cases of cervical cancer a total of 64 uterine arteries were successfully embolized and embolization, while bilateral cervical internal iliac artery and uterine artery anticancer drug perfusion, 19 cases of uterine fibroids by 3 ~ At 12-month follow-up, the average reduction rate of tumor was 59.4%. Some small fibroids disappeared and one patient died of necrosis and clinical symptoms were significantly improved. Surgical resection was successful in 13 cases of cervical cancer three weeks after operation, Cancer nest tends to disappear, the surrounding tissue lymphocytes infiltration, some of the cervix returned to normal, of which 2 cases of cancer disappeared, the group of 32 patients without serious complications after interventional therapy. Conclusion: Interventional treatment of uterine fibroids safe, minimally invasive and positive effect; preoperative intervention of cervical cancer can effectively improve the surgical resection rate and reduce the recurrence rate, it is widely used in clinical.