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目的研究替硝唑用于厌氧菌感染疾病治疗的效果。方法选择１５０例厌氧菌感染病例，随机分两组，观察组１００例应用替硝唑，对照组５０例应用甲硝唑，对比观察两组的临床疗效、副反应和厌氧菌清除率。结果替硝唑与甲硝唑的有效率分别是８７．００％和７０．００％，对厌氧菌的清除率分别是８６．４０％和７１．６９％，两组有显著性差异（Ｐ＜０．０５），不良反应发生率分别为５．００％和１４．００％，两组无差异（Ｐ＜０．０５）。结论替硝唑是一种安全有效的抗厌氧菌感染的新药
Objective To study the effect of tinidazole in the treatment of anaerobic infections. Methods 150 cases of anaerobic infections were selected and randomly divided into two groups. 100 cases in the observation group were treated with tinidazole, and 50 cases in the control group were treated with metronidazole. The clinical efficacy, side effects and anaerobic clearance rate of the two groups were compared. Results The effective rates of tinidazole and metronidazole were 87.00% and 70.00%, respectively. The clearance rate of anaerobic bacteria was 86.40% and 71.69% respectively, there was a significant difference between the two groups (P <0.05). The incidences of adverse reactions were 5.00% and 14.00% respectively, with no difference between the two groups (P <0.05). Conclusion Tinidazole is a safe and effective new drug against anaerobic infections