目的：有关早老性痴呆的新药研究近几年在国外已经越来越受到重视，本文主要介绍国外目前治疗早老性痴呆病药物的研究现状及发展前景。方法：通过综述国外有关早老性痴呆病新药研究的资料文献，把早老性痴呆病药物分成４大类进行综述。结果：目前临床用于治疗早老性痴呆病的药物主要是乙酰胆碱酯酶抑制剂类药物。促进乙酰胆碱释放的药物目前正处于不同期的临床研究阶段，或已完成临床研究。结论：β淀粉样肽可能是导致早老性痴呆病发病的直接原因，因此抗β淀粉样肽药物是研究治疗早老性痴呆病药物的一个主要研究方向 OBJECTIVE: New drug research on Alzheimer’s disease has drawn more and more attention in foreign countries in recent years. This paper mainly introduces the current research status and development prospect of Alzheimer’s disease treatment in foreign countries. Methods: By reviewing the literature of foreign countries on the research of new drugs for Alzheimer ’s disease, the Alzheimer’ s disease drugs are divided into four categories. Results: At present, the drugs clinically used to treat Alzheimer’s disease are mainly acetylcholinesterase inhibitors. Drugs that promote the release of acetylcholine are currently in different phases of clinical research or have completed clinical studies. Conclusion: β-amyloid peptide may be the direct cause leading to the pathogenesis of Alzheimer’s disease. Therefore, anti-β-amyloid peptide drugs are one of the main research directions for the study of drugs for treating Alzheimer’s disease