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目的探究左氧氟沙星联合妇科千金片对慢性盆腔炎患者炎性因子的影响。方法 110例慢性盆腔炎患者,随机分为观察组和对照组,各55例。观察组患者给予左氧氟沙星联合妇科千金片治疗,对照组患者仅给予左氧氟沙星治疗。比较两组疗效。结果观察组总有效率为92.7%,显著高于对照组的72.7%,差异具有统计学意义(P<0.05);治疗后,观察组白带增多、子宫或附件压痛、盆腔积液发生率均显著低于对照组,差异具有统计学意义(P<0.05);治疗后,观察组白细胞介素(IL)-2、IL-4、IL-10水平均显著高于对照组,肿瘤坏死因子-α(TNF-α)水平显著低于对照组,差异具有统计学意义(P<0.05)。结论采用左氧氟沙星联合妇科千金片治疗慢性盆腔炎,可显著改善临床症状,抑制盆腔慢性炎症,具有良好疗效与安全性,值得临床推广采用。
Objective To investigate the effects of levofloxacin combined with gynecological Qianjin tablets on inflammatory factors in patients with chronic pelvic inflammatory disease. Methods A total of 110 patients with chronic pelvic inflammatory disease were randomly divided into observation group and control group with 55 cases each. Patients in the observation group were treated with levofloxacin and gynecology daughter gold tablets, and patients in the control group were treated with levofloxacin only. Compare the two groups curative effect. Results The total effective rate in the observation group was 92.7%, which was significantly higher than that in the control group (72.7%) (P <0.05). After treatment, the observation group had more leucorrhea, tenderness in the uterus or appendix and pelvic effusion (P <0.05). After treatment, the levels of interleukin (IL) -2, IL-4 and IL-10 in the observation group were significantly higher than those in the control group. The levels of tumor necrosis factor-α (TNF-α) was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion Levofloxacin combined with gynecological Qianjin tablets in the treatment of chronic pelvic inflammatory disease can significantly improve clinical symptoms and inhibit chronic pelvic inflammation with good curative effect and safety, which is worthy of clinical promotion.