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以酚红血浓度变化为指标,比较经不同时间不同剂量包甲素组与正常对照组及肾损害组所引起的酚红药代动力学参数的差别。结果提示用包甲素后10分钟组对酚红参数的影响大于5小时组。
The change of phenol red blood concentration was used as an index to compare the difference of pharmacokinetic parameters of phenol red caused by different doses of Baotin Su and normal control group and renal damage group at different times. The results suggest that the effect of phenol red parameter on the phenol red parameter is greater than that of the 5-hour group after 10 minutes.