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众所周知,植物神经系统在鼻变态反应的发生中起重要作用。然而许多有关植物神经感受器的分布以及对鼻变态反应的发生所起的怍用仍不甚清楚。为回答这些问题,作者做了不同的亲植物神经系统的药物对鼻粘膜直接作用和变应性鼻炎病人对变应原的反应的药物影响的试验。方法:清除过量的鼻腔分泌物后,先测量鼻道阻力,然后用喷雾器将药物或盐水各0.26ml喷入双鼻腔,当喷嚏出现后记录次数,分泌物以鼻流量器收集,15分钟后再测量鼻道阻力并记录治疗前后的变化。其次检查药物对鼻刺激物反应的效果。亦清除过量鼻分泌物,测量鼻道阻力,接着双鼻腔喷入0.26ml的盐水,15分钟后以含有变应原的纸板刺激双下鼻甲,10分钟后检查鼻道阻力、鼻分泌物量和喷嚏次数。次日用药物取代盐水同法重复试验,记录并对比
It is well-known that the autonomic nervous system plays an important role in the development of allergic rhinitis. However, much is still unclear about the distribution of autonomic nerve receptors and the use of nasal allergy. To answer these questions, the authors have done experiments on the effects of different pro-autonomic nervous system drugs on the nasal mucosal immediate effects and the drug effects of allergen on patients with allergic rhinitis. Methods: After removing excess nasal secretions, nasal resistance was measured and then sprayed into the nasal cavity with 0.26ml of drug or saline each time the sneeze appeared. The secretions were collected with a nasal flowmeter and 15 minutes later Nasal resistance was measured and changes before and after treatment were recorded. Second, check the effect of drugs on nasal irritants. Excess nasal secretions were also cleared, nasal resistance measured, followed by two nasal sprays of 0.26 ml saline, 15 minutes after stimulation of the double inferior turbinate with allergen-containing cardboard, and 10 minutes later the nasal resistance, nasal discharge, and sneezing frequency. The next day the same method to replace the salt water test, record and contrast