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①目的 探讨小儿L型细菌败血症(SBL)的诊断与治疗。②方法 对我院收治临床疑有败血症而普通培养无细菌生长的病儿进行高渗细菌培养,做药敏试验并用敏感抗生素进行治疗。③结果 共确定L型细菌败血症46 例,对其中36 株进行药物敏感试验。结果表明,青霉素类抗生素极不敏感,而大环内酯类、氨基甙类、先锋霉素V 等药物对L型细菌敏感性高。使用相应抗生素辅以支持疗法,治愈39例,未愈5例,2 例死于原发病。④结论 临床普通培养阴性而疑有败血症病儿,应做普通及高渗双份血培养以发现L型细菌,应用敏感抗生素治疗可取得满意疗效。
Objective To investigate the diagnosis and treatment of pediatric L-type bacterial septicemia (SBL). ② methods of clinical suspected sepsis in our hospital while the ordinary culture of children without bacterial growth for hypertonic bacterial culture, drug susceptibility testing and treatment with sensitive antibiotics. ③ Results A total of 46 cases of L-type bacterial sepsis were identified, of which 36 were susceptible to drug-susceptibility testing. The results showed that penicillin antibiotics are extremely insensitive, while macrolides, aminoglycosides, such as cephalosporin V and other drugs on the L-type bacteria high sensitivity. Use the appropriate antibiotics supplemented with supportive therapy, cure 39 cases, healed in 5 cases, 2 cases died of the primary disease. ④ Conclusion Common clinical negative and suspected septicemia children should be done ordinary and hypertonic double blood culture to find L-type bacteria, the application of sensitive antibiotics can be obtained satisfactory results.