神经活性类固醇是神经组织中具有活性的类固醇,是一种内源性神经调节物质,它可以在脑、肾上腺、卵巢和睾丸中再合成,主要包括孕酮、去氧皮质酮、脱氢表雄酮(DHEA)、睾酮及其代谢产物。神经活性类固醇在治疗癫癎、外伤性脑损伤、抑郁症等神经精神疾病中的价值越来越受到人们的重 Nerve active steroid is an active steroid in nerve tissue. It is an endogenous neuromodulator which can be re-synthesized in the brain, adrenal gland, ovary and testis, mainly including progesterone, deoxycorticosterone and dehydroepiandrosterone Ketone (DHEA), testosterone and its metabolites. The value of neuroactive steroids in the treatment of neuropsychiatric disorders such as epilepsy, traumatic brain injury, depression and the like has become more and more important.