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目的探讨立体定向治疗在功能区皮层下小肿瘤性癫痫中的应用方法、治疗效果及术后并发症发生情况。方法回顾性分析2011年6月~2016年5月我院神经外科收治的功能区皮层下小肿瘤性癫痫患者67例,通过立体定向进行功能区皮层下靶向微创手术的35例患者为观察组,通过开颅手术进行肿瘤切除的32例患者为对照组,比较两组患者手术效果及术后并发症。结果随访2~36个月,观察组患者立体定向术后总有效率97.2%显著高于对照组患者总有效率75.0%(P<0.05);立体定向手术6个月后进行随访,结果显示病灶全切的满意率为94.2%高于次全切、部分切除的满意率68.6%(P<0.05)。结论原发性脑肿瘤是引发癫痫的常见因素,采用立体定向对脑功能区皮层下小肿瘤及其至痫灶进行切除,不仅可以对病灶进行精准定位,还能够有效的减少对脑功能区的损伤,均有精确、微创的优势。
Objective To investigate the application of stereotactic treatment in small tumor epilepsy with functional sub-region, therapeutic effect and postoperative complications. Methods A retrospective analysis of 67 patients with subcortical small tumor epilepsy in functional area admitted from June 2011 to May 2016 in our department of neurosurgery was performed and 35 patients underwent targeted minimally invasive surgery under the functional cortical area by stereotactic direction were observed Group, 32 patients underwent craniotomy for tumor resection as control group, and the surgical effects and postoperative complications were compared between the two groups. Results The follow-up ranged from 2 to 36 months. The total effective rate of stereotactic surgery was 97.2% in the observation group was significantly higher than that of the control group (75.0%) (P <0.05). The patients were followed up after 6 months of stereotactic surgery. The results showed that the lesions Full satisfaction rate was 94.2% higher than subtotal resection, partial resection satisfaction rate was 68.6% (P <0.05). Conclusions Primary brain tumor is a common cause of epilepsy. Stereotactic resection of small tumor and its epileptic foci in the cerebral functional area can not only locate the lesion accurately, but also effectively reduce the damage to the brain functional area Injury, are accurate, minimally invasive advantages.