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根据生成红细胞血清对免疫过程的影响资料,推测红细胞分解产物对免疫应答可能也有作用。因此红细胞分解产物不仅参与红细胞生成,而且可能也参与免疫发生的调节。本文报道腹腔注射红细胞分解产物或基质成分对白鼠免疫过程的影响。对照组注射未破坏的红细胞或生理盐水。结果证实:注射红细胞溶解物可以使白鼠对绿脓杆菌和鼠伤寒杆菌感染的抵抗力增强,死亡率下降;血球凝集素和空斑形成细胞水平升高;溶菌酶和β-溶素含量与对照组无明显差异,但血清杀菌活性和补体活性增强;粒细胞吞噬大肠杆菌的能力与对照组相同,但消化能力增强。注射红细胞溶解物致敏大鼠巨噬细胞对肿瘤细胞生长的抑制作用比对照组明
According to the information on the impact of the production of erythrocyte serum on the immune process, it is speculated that the erythrocyte decomposition products may have an effect on the immune response. Therefore, erythrocyte decomposition products are not only involved in erythropoiesis, but may also be involved in the regulation of immune development. This article reports the effects of intraperitoneal injection of erythrocyte decomposition products or matrix components on immune processes in mice. The control group was injected with undamaged red blood cells or normal saline. The results showed that: injection of erythrocyte lysate can make white mice infected with Pseudomonas aeruginosa and Salmonella typhimurium increased resistance, mortality decreased; hemagglutinin and plaque-forming cell levels increased; lysozyme and β-lysine content and control There was no significant difference between the two groups, but the serum bactericidal activity and complement activity were enhanced. The ability of granulocytes to swallow Escherichia coli was the same as that of the control group, but their digestive ability was enhanced. Injecting erythrocytes lysate sensitized rat macrophages on tumor cell growth inhibition than the control group Ming