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自1968年Cord和Fridovich阐明超氧化物歧化酶(Superoxid dismutase称SOD)具有清除超氧自由基(O(?))的特异作用以来,对其研究的发展十分迅速,然而用于对急性心肌梗塞(称AMI)的临床研究报道甚少。本文用微量快速测定法,检测AMI患者全血Cu-ZnSOD的活力,研究它对AMI的早期诊断和病情判断的价值。 对象和方法 一、对象 1.AMI组:选我院自1989年10月至1990年7月符合WHO诊断标准的住院AMI患者30例。年龄:26岁、44岁各1例,45～64岁22例,65～76岁6例;男28例、女2例。梗塞部位:单面梗塞21例:下壁8例,前间壁8例,广泛前壁3例,前壁和内膜下梗塞各1例;多面梗塞9例:前壁+高侧壁+右室和前壁+高侧壁
Since 1968, Cord and Fridovich have clarified that Superoxide dismutase (SOD) has been shown to have a specific role in scavenging superoxide radical (O (?)) And its development has been rapidly developed. However, it has been used to treat acute myocardial infarction (Called AMI) clinical research reported little. In this study, the rapid determination of trace amounts of Cu-ZnSOD in patients with AMI was used to detect the activity of Cu-ZnSOD in AMI patients and its value in the early diagnosis and diagnosis of AMI. Objects and Methods 1. Object 1. AMI group: 30 patients with AMI who met the WHO diagnostic criteria from October 1989 to July 1990 in our hospital. Age: 26 years old, 44 cases each in 1 case, 45 to 64 years in 22 cases, 65 to 76 years in 6 cases; 28 males and 2 females. Infarction site: 21 cases of single-sided infarction: 8 cases of inferior wall, anterior wall in 8 cases, extensive anterior wall in 3 cases, anterior and subintimal infarction in 1 case; multi-faceted infarction in 9 cases: anterior wall + And front wall + high side wall