Retrovirus—mediated herpes simplex virus thymidine kinase gene therapy approach for hepatocellular c

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The therapeutic effect of herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV) system on hepatocellular carcinoma was studied in this experiment.The tk-containing retroviral recombinants were used to infect hepatoma cells (BEL-7402) and the cell
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