周效磺胺(SDM~2)临床应用后尚未遇到严重过敏反应。但我们遇到2例皆系服周效磺胺过程中发生反应,且在反应发生后并未停服,反而加服本药,而引起严重过敏反应。为吸取教训,防止类似情况发生,特报告于后。例一,住院号76～1208,女性,20岁,学生,为予防“流脑”,分别于76年2月1日、8日及15日各服周效磺胺0.5克。2 Weekly Sulfanilamide (SDM ~ 2) clinical application has not yet encountered a serious allergic reaction. However, we encountered two cases all the clothes during the reaction of sulfasalazine, and after the reaction did not stop taking, but add the drug, causing serious allergic reactions. To learn lessons to prevent a similar situation, special report later. Example 1, hospitalization number 76 ~ 1208, female, 20 years old, student, to prevent “meningitis”, on February 1, 76, respectively, 2