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目的观察抗病毒药物治疗艾滋病患者体内病毒数量变化情况,从而评价治疗效果。方法32例接受HAART的艾滋病人于治疗0、6、12、18和24个月HIV病毒载量进行检测,并进行随访调查。结果接受治疗的艾滋病人治疗0个月和治疗后病毒载量差异有统计学意义,而治疗后各个时间点的病毒载量差异无统计学意义。治疗后大部分病人的病毒载量水平低于检测下限,依从性差和耐药对病毒下降有影响。结论大部分艾滋病人接受国家抗病毒药物治疗的效果明显,但随着治疗时间延长,病毒数量有反弹现象,值得关注。
Objective To observe the changes of virus in patients with AIDS treated by antiviral drugs and to evaluate the therapeutic effect. Methods 32 cases of AIDS patients receiving HAART were tested for HIV viral load at 0, 6, 12, 18 and 24 months after treatment and follow-up survey was conducted. Results The AIDS patients treated for 0 months had statistically significant differences in the viral load after treatment and after treatment, but there was no significant difference in the viral load at all time points after treatment. Most patients after treatment, the level of viral load below the detection limit, poor compliance and resistance to the impact of the virus. Conclusion Most AIDS patients have obvious effect of receiving national antiviral drugs. However, with the prolongation of treatment time, the number of viruses rebounds, which deserves our attention.