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近几年来，线粒体ＤＮＡ突变是导致母系遗传性耳聋的原因之一，从分子水平上探讨ｍｔＤＮＡ突变的发生情况，阐明突变ｍｔＤＮＡ的传递规律及线粒体ＤＮＡ与核ＤＮＡ的相互关系，都有助于揭开遗传性耳聋的本质。
In recent years, mitochondrial DNA mutation is one of the reasons leading to maternal hereditary deafness. To explore the occurrence of mtDNA mutations at the molecular level, clarify the rules of mtDNA transmission and the relationship between mitochondrial DNA and nuclear DNA, Open the nature of genetic deafness.