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药物代谢是在代谢酶催化下完成的 ,它决定着药物的药理学和毒理学特性。根据动物实验来预测人体的药物代谢时 ,代谢酶的种属差异性会使这项研究工作变得非常困难。本文对含有人体代谢酶系的重组技术模型的应用进行了介绍和评价。从而有助于预测新药在人体中的代谢机制
Drug metabolism is catalyzed by metabolic enzymes, which determine the pharmacological and toxicological properties of the drug. According to animal experiments to predict the body’s drug metabolism, species differences in metabolic enzymes make the work of this research has become very difficult. This article describes and evaluates the application of a recombinant technology model containing human metabolic enzymes. Thus helping to predict the metabolism of new drugs in the human body