目的 :观察国产泮托拉唑、胶体果胶铋 (CBP)和呋喃唑酮三联疗法根除幽门螺杆菌 (Hp)的疗效及不良反应。 方法 :把确诊为Hp感染的 6 0例消化性溃疡 (PU)病人随机分为 2组 ,A组 32例给予泮托拉唑、CBP和呋喃唑酮治疗。B组 2 8例给予奥美拉唑、克拉霉素和甲硝唑治疗。 2组疗程均 14d。治疗期间分别观察 2组药物不良反应。结果 :A组Hp根除率为93.5 % ,B组 92 .8% ,无显著性差异。而不良反应发生率A组明显少于B组。结论 :使用A组药物治疗Hp感染的PU ,疗效肯定 ,不良反应少。 Objective: To observe the efficacy and side effects of domestic pantoprazole, colloidal pectin bismuth (CBP) and furazolidone triple therapy in the eradication of Helicobacter pylori (Hp). Methods: Sixty patients with peptic ulcer (PU) diagnosed as Hp infection were randomly divided into two groups. Group A received pantoprazole, CBP and furazolidone treatment. B group 28 cases were given omeprazole, clarithromycin and metronidazole treatment. 2 groups of treatment are 14d. Two groups of adverse drug reactions were observed during treatment. Results: The Hp eradication rate was 93.5% in group A and 92.8% in group B, with no significant difference. The incidence of adverse reactions in group A was significantly less than in group B. Conclusion: A group of drugs used to treat Hp infection PU, positive effect, fewer adverse reactions.