目的明确阴道镜下宫颈定位电切活检是否比宫颈常规四点(30,60,90,120)活组织检查更有应用价值,探讨阴道镜下宫颈定位电切活检在宫颈上皮内瘤变(C IN)诊断中的价值。方法回顾性分析近2年来,因宫颈病变行宫颈细胞学及阴道镜检查均异常者88例。需行宫颈活检者,其中宫颈常规活检44例,阴道镜定位活检44例。采用对照法,对比分析宫颈常规四点活检及阴道镜下定位电切活检的病理检查结果。结果宫颈常规四点活检与阴道镜下定位电切活检的病理结果完全符合者31例(35.2%),不符合者57例(64.8%)。其中病理级别阴道镜下定位电切活检较宫颈常规四点活检升高16例(18.2%),宫颈阴道镜下定位电切活检发现C IN3及宫颈原位癌共8例,早期浸润癌2例,均予子宫切除术及广泛子宫切除术。病理报告为C IN2者32例,行宫颈锥切术,术后并重新病检,切缘干净。C IN118例,行宫颈电熨术。在平均18个月的随诊期间,无1例出现宫颈细胞学检查异常,宫颈电切取活检及常规四点取活检的主要并发症为术后出血。结论阴道镜下定位电切活检较宫颈常规四点活检更有应用价值,同时也可作为治疗的一种方法。因病变组织在取活检时已被整块切除,而宫颈常规四点活检无法做到这一点。 Objective To determine whether colposcopic cervical biopsy is more useful than conventional four-point (30, 60, 90, 120) biopsy of the cervix. To investigate the value of colposcopic biopsy in cervical intraepithelial neoplasia (CIN) Diagnostic value. Methods Retrospective analysis of the past two years, due to cervical lesions cervical cytology and colposcopy were abnormal in 88 cases. Cervical biopsy should be performed, including routine cervical biopsy in 44 cases, 44 colposcopy biopsy. Contrast analysis of cervical biopsy and colposcopic biopsy biopsy pathological examination results using comparative method. Results The biopsy results of cervical routine biopsy and colposcopic biopsy were 31 (35.2%) and 57 (64.8%) respectively. Pathological grade colposcopic mapping biopsy than the conventional cervical biopsies increased 16 cases (18.2%), Cervical colposcopic mapping biopsy found C IN3 and cervical carcinoma in situ in 8 cases, early invasive carcinoma in 2 cases , Were given hysterectomy and extensive hysterectomy. 32 cases of pathological report of C IN2, cervical conization, postoperative and re-pathological examination, clean margins. C IN118 cases, cervix electric iron. During an average of 18 months of follow-up, none of the patients had abnormal cervical cytology. The major complication of biopsy of the cervix and conventional biopsies was postoperative bleeding. Conclusion colposcopic mapping of biopsy than conventional cervical biopsy more practical value, but also can be used as a method of treatment. Due to diseased tissue in the biopsy has been a complete excision, and cervical biopsy routine can not do this.