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二(口恶)英是一类含有两个氧原子连结二苯环(C_(12)H_8O_2)物质的总称。其中2,3,7,8-四氯二苯基-对-二(口恶)英(TCDD)对人类健康的影响是人们当前所关心的。TCDD是除莠剂(2,4,5-三氯苯氧基醋酸)(2,4,5-T)的污染物。Agent Orange是2,4,5-T的正丁酯和二氯苯氧基醋酸、(2,4-D)两种物质的混合物(50∶50),在越南曾用作脱叶剂和庄稼毁灭剂。近二十年以来,2,4,5-T广泛用于控制树木和杂草的过度生长。 TCDD对实验动物有很强的急性毒性,对小鼠是胚胎毒剂和致畸剂。1977年IARC(国际癌症研究机构)的一个研究组认为“根据现有资料尚难对氯代二苯基二(口恶)英类的致癌性做
Two (evil) British is a class containing two oxygen atoms linked diphenyl ring (C_ (12) H_8O_2) the general term. Among them, 2,3,7,8-tetrachlorodiphenyl-p-dioxins (TCDD) affect the human health is currently of concern. TCDD is a contaminant of the herbicide (2,4,5-trichlorophenoxyacetic acid) (2,4,5-T). Agent Orange is a mixture of n-butyl 2,4,5-T and dichlorophenoxyacetic acid (2,4-D) (50:50), which was used as defoliants and crops in Vietnam Destroyer. For nearly two decades 2,4,5-T has been widely used to control the overgrowth of trees and weeds. TCDD has strong acute toxicity to laboratory animals, and is an embryo toxin and teratogen to mice. A 1977 IARC (International Agency for Research on Cancer) study group concluded that "it is difficult to make carcinogenicity to chlorodiphenyl di (catecholam) based on available information