松果体的分泌物褪黑激素(melatonin)能抑制新生大鼠垂体或垂体培养液的黄体生成素(LH)和卵泡刺激素(FSH)对促性腺素释放激素(LHRH)的反应。作者在本研究中企图验证褪黑激素对促性腺细胞是直接抑制作用或需要垂体的其它细胞参与。实验是用初生15天的Sprague-Dawley雌性大鼠。用细胞培养的方法观察垂体细胞对LHRH和褪黑激素的反应。分散的垂体细胞制备是在 The melatonin, a secretor of the pineal gland, inhibits the response of luteinizing hormone (LH) and follicle stimulating hormone (FSH) to gonadotropin-releasing hormone (LHRH) in the pituitary or pituitary cultures of neonatal rats. In this study, the authors attempted to demonstrate that melatonin is directly involved in the inhibition of gonadal cells or other cells that require pituitary gland. Experiments were performed on Sprague-Dawley female rats of 15 days newborn. The cell culture method was used to observe the response of pituitary cells to LHRH and melatonin. Scattered pituitary cells are prepared